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молекула L-arginine
молекула L-arginine

Нобелевские лауреаты 1998 года:

Ф.Ферчготт

Л.Игнарро

Ф.Мурад

аргинин по 1000 мг 90 капсул производства Solgar

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аргинин по 1000 мг 90 капсул производства Solgar

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Список англоязычных публикаций за 2006 год об аргинине:

декабрь

  1. Early response to venlafaxine antidepressant correlates with lower ACTH levels prior to pharmacological treatment.
  2. Early left ventricular gene expression profile in response to increase in blood pressure.
  3. Serum bone markers in patients with loosening of cemented total hip endoprosthesis
  4. Evaluation of bone metabolism in patients after total hip replacement based on bone turnover markers
  5. Clinical trials of new therapeutic pharmacology for sickle cell disease
  6. Pituitary apoplexy: retrospective review of 30 patients--is surgical intervention always necessary?
  7. Effects of 5-hydroxytryptamine on electrical responses of circular smooth muscle isolated from the guinea-pig gastric antrum.
  8. Effects of Dai-kenchu-to on spontaneous activity in the mouse small intestine.
  9. Nitric oxide modulates biphasic contractile response of guinea pig vas deferens to electrical field stimulation.
  10. The cytokine profile during experimental esophagitis and modification of cytoprotective mechanisms.
  11. A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC).
  12. A general user interface for prediction servers of proteins' post-translational modification sites.

ноябрь

  1. Evaluation of tissue-engineered vascular autografts.

октябрь

  1. Effect of activated protein C on secretory activity of rat peritoneal mast cells.
  2. Peculiarities of autonomic regulation assessed by variability of hemodynamic parameters in rats with different stress resistance.

сентябрь

август

июль

июнь

  1. Site-specific synthesis of Amadori-modified peptides on solid phase.
  2. Alteration of decreased plasma NO metabolites and platelet NO synthase activity by paroxetine in depressed patients.

май

  1. Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix.
  2. Mutations in alpha-helical solvent-exposed sites of eglin c have long-range effects: evidence from molecular dynamics simulations.

апрель

  1. Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor.
  2. Investigation of mechanism of desmopressin binding in vasopressin V2 receptor versus vasopressin V1a and oxytocin receptors: molecular dynamics simulation of the agonist-bound state in the membrane-aqueous system.
  3. Activation of classical protein kinase C reduces the expression of human cationic amino acid transporter 3 (hCAT-3) in the plasma membrane.

март

  1. Mucopolysaccharidosis type IV: N-acetylgalactosamine-6-sulfatase mutations in Tunisian patients.
  2. Gut-trophic feed additives and their effects upon the gut structure and intestinal metabolism. State of the art in the pig, and perspectives towards humans.
  3. Biochemical properties of recombinant human and mouse N-acetylglutamate synthase.
  4. Protein design simulations suggest that side-chain conformational entropy is not a strong determinant of amino acid environmental preferences.
  5. Regional heterogeneity in the haemodynamic responses to urotensin II infusion in relation to UT receptor localisation.

февраль

  1. Carbopol-mediated paracellular transport enhancement in Calu-3 cell layers.
  2. Growth hormone deficiency after chemotherapy for acute lymphoblastic leukemia in children who have not received cranial radiation.
  3. The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.
  4. Tyrosine hydroxylase-synthesizing cells in the hypothalamus of prairie voles (Microtus ochrogaster): sex differences in the anteroventral periventricular preoptic area and effects of adult gonadectomy or neonatal gonadal hormones.
  5. Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues.

январь

  1. Depletion of intracellular Ca2+ stores enhances flow-induced vascular dilatation in rat small mesenteric artery.
  2. Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA.
  3. Surfactant as an airway smooth muscle relaxant.
  4. Nickel deficiency disrupts metabolism of ureides, amino acids, and organic acids of young pecan foliage.
  5. S-glutathiolation by peroxynitrite of p21ras at cysteine-118 mediates its direct activation and downstream signaling in endothelial cells.
  6. Hypoxia promotes relaxation of bovine coronary arteries through lowering cytosolic NADPH.
  7. Polyamines induce rapid biosynthesis of nitric oxide (NO) in Arabidopsis thaliana seedlings.
  8. Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes.
  9. Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as potential inhibitors for HIV TAR-Tat.
  10. Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription.
  11. Nitric oxide production from rat adipocytes is modulated by beta3-adrenergic receptor agonists and is involved in a cyclic AMP-dependent lipolysis in adipocytes.
  12. Arginine vasotocin (AVT) and isotocin (IT) in fish brain: diurnal and seasonal variations.
  13. Determination of free amino acids and related compounds in amniotic fluid by capillary electrophoresis with contactless conductivity detection.
  14. Intermedin/adrenomedullin-2 dilates the rat pulmonary vascular bed: dependence on CGRP receptors and nitric oxide release.
  15. The functional integrity of a normothermic perfusion system using artificial blood in pig liver.
  16. Dissociation and unfolding of inducible nitric oxide synthase oxygenase domain identifies structural role of tetrahydrobiopterin in modulating the heme environment.
  17. Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats.
  18. Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling.
  19. Stress history and pubertal development interact to shape hypothalamic-pituitary-adrenal axis plasticity.
  20. Bioinformatic analysis of an unusual gene-enzyme relationship in the arginine biosynthetic pathway among marine gamma proteobacteria: implications concerning the formation of N-acetylated intermediates in prokaryotes.
  21. Angiotensin II does not affect endothelial tone in Type 1 diabetes-results of a double-blind placebo controlled trial.
  22. Case report: Avoidance of palpable corporal fibrosis due to priapism with upregulators of nitric oxide.
  23. Identification of microcystin toxins from a strain of Microcystis aeruginosa by liquid chromatography introduction into a hybrid linear ion trap-Fourier transform ion cyclotron resonance mass spectrometer.
  24. Arginine uptake is attenuated through modulation of cationic amino-acid transporter-1, in uremic rats.
  25. Protection against myocardial ischaemia/reperfusion injury by PPAR-alpha activation is related to production of nitric oxide and endothelin-1.
  26. In hepatocytes the regulation of NOS-2 activity at physiological L-arginine levels suggests a close link to the urea cycle.
  27. Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.
  28. Exchange of glutamine-217 to glutamate of Clostridium limosum exoenzyme C3 turns the asparagine-specific ADP-ribosyltransferase into an arginine-modifying enzyme.
  29. Through the central V2, not V1 receptors influencing the endogenous opiate peptide system, arginine vasopressin, not oxytocin in the hypothalamic paraventricular nucleus involves in the antinociception in the rat.
  30. Arginase strongly impairs neuronal nitric oxide-mediated airway smooth muscle relaxation in allergic asthma.
  31. New Strategies for the Treatment of Pulmonary Hypertension in Sickle Cell Disease : The Rationale for Arginine Therapy.
  32. Heterologous expression and characterization of a novel branching enzyme from the thermoalkaliphilic anaerobic bacterium Anaerobranca gottschalkii.
  33. Renal ENaC subunit, Na-K-2Cl and Na-Cl cotransporter abundances in aged, water-restricted F344 x Brown Norway rats.
  34. Supplemental conditionally essential nutrients in cardiovascular disease therapy.
  35. Evidence for functional conservation, sufficiency, and proteolytic processing of the CLAVATA3 CLE domain.
  36. Serine/arginine-rich splicing factors belong to a class of intrinsically disordered proteins.
  37. Carbon catabolite repression regulates amino acid permeases in Saccharomyces cerevisiae via the TOR signaling pathway.
  38. Sumoylation inhibits cleavage of Sp1 N-terminal negative regulatory domain and inhibits Sp1-dependent transcription.
  39. Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.
  40. Structure and reactivity of a thermostable prokaryotic nitric-oxide synthase that forms a long-lived oxy-heme complex.
  41. Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons.
  42. Hypersensitivity of prediabetic JCR:LA-cp rats to fine airborne combustion particle-induced direct and noradrenergic-mediated vascular contraction.
  43. Does central nitric oxide elicit pulmonary hypertension in conscious rats?
  44. Involvement of nitric oxide pathway in the acute anticonvulsant effect of melatonin in mice.
  45. Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta.
  46. Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function.
  47. Identification of open reading frames unique to a select agent: Ralstonia solanacearum race 3 biovar 2.
  48. Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME.
  49. Belnapia moabensis gen. nov., sp. nov., an alphaproteobacterium from biological soil crusts in the Colorado Plateau, USA.
  50. Arginine- and lysine-specific polymers for protein recognition and immobilization.
  51. A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome.
  52. A SALL4 zinc finger missense mutation predicted to result in increased DNA binding affinity is associated with cranial midline defects and mild features of Okihiro syndrome.
  53. Alteration of the stereo- and regioselectivity of alkene monooxygenase based on coupling protein interactions.
  54. The discovery of nitric oxide and its role in vascular biology.
  55. Role of NK1 and NK2 receptors in mouse gastric mechanical activity.
  56. Enhanced superoxide activity modulates renal function in NO-deficient hypertensive rats.
  57. Hepatic venous dysregulation contributes to blood volume pooling in cirrhotic rats.
  58. Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease.
  59. activated polyamine catabolism in acute pancreatitis: alpha-methylated polyamine analogues prevent trypsinogen activation and pancreatitis-associated mortality.
  60. Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
  61. Exercise training improves femoral artery blood flow responses to endothelium-dependent dilators in hypercholesterolemic pigs.
  62. Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine.
  63. Mutation in the epsilon subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct5) gene causes autosomal recessive mutilating sensory neuropathy with spastic paraplegia.
  64. Ventilator-induced lung injury is reduced in transgenic mice that overexpress endothelial nitric oxide synthase.
  65. Nitric oxide augments fetal pulmonary artery endothelial cell angiogenesis in vitro.
  66. Effect of nitric oxide and peroxynitrite on mucociliary transport function of experimental otitis media.
  67. Catecholamines and vasopressin during critical illness.
  68. Crataegus tanacetifolia leaf extract prevents L-NAME-induced hypertension in rats: a morphological study.
  69. Constitutive arginine-dependent nitric oxide synthase activity in different organs of pea seedlings during plant development.
  70. Interplay between two hormone-independent activation domains in the androgen receptor.
  71. Prenatal exposure to dexamethasone alters hippocampal drive on hypothalamic-pituitary-adrenal axis activity in adult male rats.
  72. Renal effects of human urotensin-II in rats with experimental congestive heart failure.
  73. Endothelin-induced increased nitric oxide mediates augmented distal nephron acidification as a result of dietary protein.
  74. Genetic AVP deficiency abolishes cold-induced diuresis but does not attenuate cold-induced hypertension.
  75. Effect of diet and omega-3 fatty acid intervention on asymmetric dimethylarginine.
  76. The role of melanocyte-stimulating hormone in insulin resistance and type 2 diabetes mellitus.
  77. Phosphate stabilization of intermolecular interactions.
  78. Regulation of citB expression in Bacillus subtilis: integration of multiple metabolic signals in the citrate pool and by the general nitrogen regulatory system.
  79. Effect of L-arginine on pulmonary artery smooth muscle cell apoptosis in rats with hypoxic pulmonary vascular structural remodeling.
  80. Epimedium brevicornum Maxim extract relaxes rabbit corpus cavernosum through multitargets on nitric oxide/cyclic guanosine monophosphate signaling pathway.
  81. Mechanism of hepatic heme oxygenase-1 induction by isoflurane.
  82. Effects of poly-L-arginine on the permeation of hydrophilic compounds through surface ocular tissues.
  83. Anti-inflammatory effect of propolis through inhibition of nitric oxide production on carrageenin-induced mouse paw edema.
  84. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils.
  85. L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.
  86. Vasorelaxing effect of BAY 41-2272 in rat basilar artery: involvement of cGMP-dependent and independent mechanisms.
  87. Effect of simultaneous inoculation with yeast and bacteria on fermentation kinetics and key wine parameters of cool-climate chardonnay.
  88. The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL.
  89. [Argatroban : Pharmacological properties and anaesthesiological aspects.]
  90. Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2.
  91. Adaptation to pregnancy leads to attenuated rat uterine artery smooth muscle sensitivity to oxytocin.
  92. Inhibitory effect of erythropoietin on contractility of human chorionic plate vessels.
  93. Binding modes of the precursor of adenovirus major core protein VII to DNA and template activating factor I: implication for the mechanism of remodeling of the adenovirus chromatin.
  94. Alteration of the regiospecificity of human heme oxygenase-1 by unseating of the heme but not disruption of the distal hydrogen bonding network.
  95. Delayed and persistent suppression of bronchoconstriction by trypsin in the airway lumen.
  96. Beneficial effect of amino acid supplementation, especially cysteine, on body nitrogen economy in septic rats.
  97. Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice.
  98. Growth in Stewart's medium is a simple, rapid and inexpensive screening tool for the identification of Burkholderia cepacia complex.
  99. Different signaling molecules responsible for IL-1beta-induced oxytocinergic and vasopressinergic neuron activation in the hypothalamic paraventricular nucleus of the rat.
  100. Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine.
  101. Analysis of the mechanisms underlying the vasorelaxant action of angiotensin II in the isolated rat carotid.
  102. Vasoconstrictor prostanoids may be involved in reduced coronary reactive hyperemia after ischemia-reperfusion in anesthetized goats.
  103. Anaerobic survival of Pseudomonas aeruginosa by pyruvate fermentation requires an Usp-type stress protein.
  104. Identification of Listeria monocytogenes genes contributing to intracellular replication by expression profiling and mutant screening.
  105. Structure, regulation, and putative function of the arginine deiminase system of Streptococcus suis.
  106. Potential difference measurements of ocular surface Na+ absorption analyzed using an electrokinetic model.
  107. Cooperative effect of factors governing molecular ion yields in desorption/ionization mass spectrometry.
  108. Accumulation of symmetric dimethylarginine in hepatorenal syndrome.
  109. Arginine or nitrate enhances antibiotic susceptibility of Pseudomonas aeruginosa in biofilms.
  110. The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginine.
  111. A novel R275X mutation of the SLC25A15 gene in a Japanese patient with the HHH syndrome.
  112. Conivaptan: a selective vasopressin antagonist for the treatment of heart failure.
  113. Protein stabilization by specific binding of guanidinium to a functional arginine-binding surface on an SH3 domain.
  114. The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea-pig ileum.
  115. Removal of tonic nitrergic inhibition is a potent stimulus for human proximal colonic propagating sequences.
  116. Relaxant responses to calcium channel antagonists and potassium channel opener in human saphenous vein.
  117. Unexpected similarity between the cytosolic West Nile virus NS3 and the secretory furin-like serine proteinases.
  118. Fusobacterium nucleatum transports noninvasive Streptococcus cristatus into human epithelial cells.
  119. Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells.
  120. Immune-enhancing diet and cytokine expression during chronic sepsis: an immune-enhancing diet containing L-arginine, fish oil, and RNA fragments promotes intestinal cytokine expression during chronic sepsis in rats.
  121. Reactivity of the heme-dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates.
  122. Neuronal nitric oxide synthase is necessary for elimination of Giardia lamblia infections in mice.
  123. Consumption of soy isoflavones does not affect plasma total homocysteine or asymmetric dimethylarginine concentrations in healthy postmenopausal women.
  124. Release of tritiated agmatine from spinal synaptosomes.
  125. Cause and consequences of sympathetic hyperactivity in chronic kidney disease.
  126. Evaluation of pet food by-product as an alternative feedstuff in weanling pig diets.
  127. Modulation of arginine metabolic pathways as the potential anti-tumor mechanism of recombinant arginine deiminase.
  128. Packaging of chemicals in the defensive secretory glands of the sea hare Aplysia californica.
  129. Age of diagnosis of colorectal cancer in HNPCC patients is more complex than that predicted by R72P polymorphism in TP53.
  130. Resistance to renal damage by chronic nitric oxide synthase inhibition in the Wistar-Furth rat.
  131. Role of the novel OprD family of porins in nutrient uptake in Pseudomonas aeruginosa.
  132. Nonstructural protein 3 of bluetongue virus assists virus release by recruiting ESCRT-I protein Tsg101.
  133. The Arg389Gly beta1-adrenoceptor polymorphism does not affect cardiac effects of exercise after parasympathetic inhibition by atropine.
  134. Phase matchable semiorganic NLO material for frequency doubling: L-Arginine tetrafluoroborate.
  135. Identification of peptide metabolites of Microcystis (Cyanobacteria) that inhibit trypsin-like activity in planktonic herbivorous Daphnia (Cladocera).
  136. Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.
  137. Developmental changes of nitric oxide synthase expression in the rat hypothalamoneurohypophyseal system.
  138. Effects of probiotics on the severity of experimental acute pancreatitis.
  139. Signal peptide protection by specific chaperone.
  140. Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism.
  141. Effect of 5-lipoxygenase blockade on blood pressure and acetylcholine-evoked endothelium-dependent contraction in aorta from spontaneously hypertensive rats.
  142. Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats.
  143. Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: a case control analysis.
  144. Inhibition of proliferative and invasive capacities of breast cancer cells by arginine-glycine-aspartic acid peptide in vitro.
  145. Possible vascular role of increased plasma arginine vasopressin in congestive heart failure.
  146. Prolonged ventricular action potential duration due to nitric oxide release.
  147. Base-pairing potential identified by in vitro selection predicts the kinked RNA backbone observed in the crystal structure of the alfalfa mosaic virus RNA-coat protein complex.
  148. Protective effect of nitric oxide pathway in resveratrol renal ischemia-reperfusion injury in rats.
  149. Gestational diabetes and the adenosine/L-arginine/nitric oxide (ALANO) pathway in human umbilical vein endothelium.