Аргинин.Ру - всё об аргинине  
В начало
Контакты
Рекламодателям
 


молекула L-arginine
молекула L-arginine

Нобелевские лауреаты 1998 года:

Ф.Ферчготт

Л.Игнарро

Ф.Мурад

аргинин по 1000 мг 90 капсул производства Solgar

Про аргинин:

Что такое аргинин?
Откуда берется аргинин?
Механизм действия.

Аргинин в медицине:

Сердечная недостаточн.
Стенокардия
Гипертония
Онкология (рак)
Геронтология (старение)
Атеросклероз
Травмы
Ожоги
Гормональный обмен
ВИЧ/СПИД

Где купить аргинин

аргинин по 1000 мг 90 капсул производства Solgar

Библиотека статей:




Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; SAPE_base has a deprecated constructor in /home/ih72672/public_html/arginine.ru/1152e72650d4093c1a42c7534a7d7797/sape.php on line 21

Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; SAPE_client has a deprecated constructor in /home/ih72672/public_html/arginine.ru/1152e72650d4093c1a42c7534a7d7797/sape.php on line 615

Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; SAPE_context has a deprecated constructor in /home/ih72672/public_html/arginine.ru/1152e72650d4093c1a42c7534a7d7797/sape.php on line 1177

Deprecated: Methods with the same name as their class will not be constructors in a future version of PHP; SAPE_articles has a deprecated constructor in /home/ih72672/public_html/arginine.ru/1152e72650d4093c1a42c7534a7d7797/sape.php on line 1529

Warning: Use of undefined constant _SAPE_USER - assumed '_SAPE_USER' (this will throw an Error in a future version of PHP) in /home/ih72672/public_html/arginine.ru/1152e72650d4093c1a42c7534a7d7797/sape.php on line 1090
Авторы:Somponpun SJ, Sladek CD.
Дата:2004 год, июнь.

Depletion of oestrogen receptor-beta expression in magnocellular arginine vasopressin neurones by hypovolaemia and dehydration.

  автоматический перевод
Oestrogen receptor (ER)-beta expression correlates inversely with osmotic control of arginine vasopressin (AVP) release such that cellular dehydration induced by 72 h of 2% saline consumption depletes ER-beta in the magnocellular AVP neurones in the supraoptic (SON) and paraventricular nuclei (PVN). The current studies were performed to determine whether other pathways that stimulate AVP release, such as hypovolaemia, also regulate ER-beta expression in these nuclei, and to evaluate the time course of the change in ER-beta expression during water deprivation and subsequent rehydration. ER-beta expression was evaluated immunocytochemically. In rats made hypovolaemic with a subcutaneous injection of 40% polyethylene glycol (PEG), a significant depletion of ER-beta in both SON and magnocellular PVN (P <= 0.001) was evident 8 h post PEG injection. ER-beta was also significantly depleted following 20 h and 26 h of water deprivation in SON (P = 0.003) and magnocellular PVN (P < 0.001). Six hours of rehydration in rats that had been water deprived for 26 h induced recovery of expression that was statistically significant, although not complete (P <= 0.015 in PVN). Thus, for the first time, the present studies demonstrate that haemodynamic in addition to osmotic influences are capable of regulating ER-beta expression in the magnocellular system, and that the combination of these factors induced by a physiological manipulation (e.g. 20 h of water deprivation) can eliminate ER-beta expression. Because ER-beta has been shown to mediate inhibition of AVP secretion in explants of the hypothalamic-neurohypophyseal system, these data suggest that down-regulation of ER-beta may contribute to stimulated AVP release during hypovolaemic states such as fluid deprivation and haemorrhage.   Эстроген рецептор (ER)-бета слова обратно коррелирует с осмотической контроль аргинина вазопрессина (АВП), чтобы освободить сотовой дегидратации, вызванных 72 ч 2% соленых потребления истощает ER-бета в Магноцеллюлярный AVP neurones в supraoptic (SON), и паравентрикулярного ядер (PVN). В настоящее время исследования были проведены для определения других путей стимулирования, что AVP версии, такие, как hypovolaemia, также регулируют ER-бета выражение в этих ядер, а также для оценки времени курс изменения в ER-бета выражении во время лишение воды и последующего регидратация. ER-бета выражения оценивалась immunocytochemically. У крыс сделал hypovolaemic с подкожных инъекций 40% полиэтилен гликоль (PEG), значительное истощение ER-бета в обоих SON и Магноцеллюлярный PVN (P

к списку статей за 2004 год (en)

в библиотеку