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молекула L-arginine
молекула L-arginine

Нобелевские лауреаты 1998 года:

Ф.Ферчготт

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аргинин по 1000 мг 90 капсул производства Solgar

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Библиотека статей об аргинине. Декабрь 2001. En.

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  1. Paternal behavior is associated with central neurohormone receptor binding patterns in meadow voles (Microtus pennsylvanicus).
  2. [The role of beta 3-adrenergic receptors in the human organism]
  3. Effect of low doses of L-NAME on methamphetamine-induced dopaminergic depletion in the rat striatum.
  4. Effect of an acute oral ibuprofen intake on urinary aquaporin-2 excretion in healthy humans.
  5. Evidence that the N-terminal extension of the vicieae convicilin genes evolved by intragenic duplications and trinucleotide expansions.
  6. EPR and optical absorption studies of VO2+ doped L-arginine phosphate monohydrate single crystals--part I.
  7. [Nitric oxide (NO) in the pathophysiology of asthma and interstitial lung diseases]
  8. L-Canavanine: a higher plant insecticidal allelochemical.
  9. In vitro responses of equine colonic arterial and venous rings to adenosine triphosphate.
  10. Effects of acetylpromazine or morphine on urine production in halothane-anesthetized dogs.
  11. Effect of nitric oxide synthase inhibition on the gastric mucosal barrier in rats.
  12. The ionic layer is required for efficient dissociation of the SNARE complex by alpha-SNAP and NSF.
  13. Nitric oxide in vPAG mediates the depressor response to acupuncture in stress-induced hypertensive rats.
  14. Nitric oxide synthase inhibitor and IL-18 enhance the anti-tumor immune response of rats carrying an intrahepatic colon carcinoma.
  15. Protein deficiency attenuates the effects of alloxan on insulin secretion and glucose homeostasis in rats.
  16. The perfused guinea-pig lung revisited: a study of EDRF-no system.
  17. [Inhibitors of arginase in the L-arginine metabolic pathway as a new class of antihypertensive drugs: effect of carbamide on lipid oxidative metabolism and on vessel tonus during arterial hypertension]
  18. Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans.
  19. A novel WD repeat protein component of the methylosome binds Sm proteins.
  20. Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.
  21. The nucleic acid melting activity of Escherichia coli CspE is critical for transcription antitermination and cold acclimation of cells.
  22. The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis.
  23. A Y2 receptor mimetic aptamer directed against neuropeptide Y.
  24. Antithrombin deficiency in Brazilian patients with venous thrombosis: molecular characterization of a single splice site mutation, an insertion and a de novo point mutation.
  25. Triphasic vascular responses to bradykinin in the mesenteric resistance artery of the rat.
  26. Changes in Fos expression in various brain regions during deoxycorticosterone acetate treatment: relation to salt appetite, vasopressin mRNA and the mineralocorticoid receptor.
  27. Combining multiple structure and sequence alignments to improve sequence detection and alignment: application to the SH2 domains of Janus kinases.
  28. Nitric oxide-mediated regulation of chemosensitivity in cancer cells.
  29. Role of nucleotidyl transferase motif V in strand joining by chlorella virus DNA ligase.
  30. Determinants of ligand specificity in groups I and IV WW domains as studied by surface plasmon resonance and model building.
  31. The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme.
  32. Xaa-Arg-Gly triplets in the collagen triple helix are dominant binding sites for the molecular chaperone HSP47.
  33. Isolated systolic hypertension in elderly WKY is reversed with L-arginine and ACE inhibition.
  34. Local hemodynamic changes in hypertension: insights for therapeutic preservation of target organs.
  35. Decreased nitric oxide availability in normotensive and hypertensive rats with failing hearts after myocardial infarction.
  36. Apoptosis and glomerular injury after prolonged nitric oxide synthase inhibition in spontaneously hypertensive rats.
  37. Angiotensin II induces phenotype-dependent apoptosis in vascular smooth muscle cells.
  38. Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats.
  39. Methylation at arginine 17 of histone H3 is linked to gene activation.
  40. Differential association of the codon 72 p53 and GSTM1 polymorphisms on histological subtype of non-small cell lung carcinoma.
  41. NO/cGMP signaling and HSP90 activity represses metamorphosis in the sea urchin Lytechinus pictus.
  42. Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
  43. Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro.
  44. NO mediates ginsenoside Rg1-induced long-term potentiation in anesthetized rats.
  45. A novel nonsense mutation (R269X) in the myophosphorylase gene in a patient with McArdle disease.
  46. Improving treatment of guanidinoacetate methyltransferase deficiency: reduction of guanidinoacetic acid in body fluids by arginine restriction and ornithine supplementation.
  47. Nitric oxide signals parallel fiber activity to Bergmann glial cells in the mouse cerebellar slice.
  48. Characterization of the sec1-1 and sec1-11 mutations.
  49. Growth inhibition of glioblastoma cells by human Pur(alpha).
  50. A new mutation of the arginine vasopressin-neurophysin II gene in a family with autosomal dominant neurohypophyseal diabetes insipidus.
  51. Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.
  52. Conjugative plasmid protein TrwB, an integral membrane type IV secretion system coupling protein. Detailed structural features and mapping of the active site cleft.
  53. Activation of cardiac endothelium as a compensatory component in endotoxin-induced cardiomyopathy: role of endothelin, prostaglandins, and nitric oxide.
  54. Myocardial contractile function and heart rate in mice with myocyte-specific overexpression of endothelial nitric oxide synthase.
  55. Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family.
  56. Impact of hyperthyroidism and its correction on vascular reactivity in humans.
  57. Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln.
  58. Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter.
  59. Neomycin B-arginine conjugate, a novel HIV-1 Tat antagonist: synthesis and anti-HIV activities.
  60. Mechanisms for intragenic complementation at the human argininosuccinate lyase locus.
  61. Three-dimensional structure of the argininosuccinate lyase frequently complementing allele Q286R.
  62. Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment.
  63. Antiulcerogenic activity of crude ethanol extract and some fractions obtained from aerial parts of Artemisia annua L.
  64. Spontaneous chiral separation in noncovalent molecular clusters.
  65. Stabilizing nonpolar/polar side-chain interactions in the alpha-helix.
  66. Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
  67. Role of specific activators of intestinal amino acid transport in Bombyx mori larval growth and nutrition.
  68. The natural substrate for nitric oxide synthase activity.
  69. Effect of nitric oxide on iron-mediated cytotoxicity in primary cultured renal proximal tubules.
  70. [Interdisciplinary treatment of early-onset ornithine transcarbamylase (OTC) deficiency. Two case reports and a review]
  71. Hypersensitivity of pulmonary C fibre afferents induced by cationic proteins in the rat.
  72. Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.
  73. University of Wisconsin solution increases hyperpolarizing mechanisms in response to bradykinin.
  74. Critical role of the neuronal nitric-oxide synthase heme proximal side residue, Arg418, in catalysis and electron transfer.
  75. Nitric oxide mediates leptin-induced preovulatory luteinizing hormone and prolactin surges in rats.
  76. In vitro stimulation of oxidative stress in cerebral cortex of rats by the guanidino compounds accumulating in hyperargininemia.
  77. Extracellular glutamate, aspartate and arginine increase in the ventral posterolateral thalamic nucleus during nociceptive stimulation.
  78. Effects of nitric oxide and GABA interaction within ventrolateral medulla on cardiovascular responses during static muscle contraction.
  79. Water permeation across biological membranes: mechanism and dynamics of aquaporin-1 and GlpF.
  80. Dietary protein peptic hydrolysates stimulate cholecystokinin release via direct sensing by rat intestinal mucosal cells.
  81. Association of BMI with the beta3-adrenergic receptor gene polymorphism in Japanese: meta-analysis.
  82. Secondhand tobacco smoke impairs rabbit pulmonary artery endothelium-dependent relaxation.
  83. Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells.
  84. RGD peptides and monoclonal antibodies, antagonists of alpha(v)-integrin, enter the cells by independent endocytic pathways.
  85. Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor.
  86. Q/R RNA editing of the AMPA receptor subunit 2 (GRIA2) transcript evolves no later than the appearance of cartilaginous fishes.
  87. Role of glucocorticoid hormones in arginine vasopressin gene regulation.
  88. Low molecular weight protamine (LMWP) as nontoxic heparin/low molecular weight heparin antidote (I): preparation and characterization.
  89. Effect of progesterone on peripheral blood flow in prepubertal female anesthetized pigs.
  90. Effects of systemic blockade of nitric oxide synthases on pulsatile LH, prolactin, and GH secretion in adult male rats.
  91. Increases in plasma ACTH and cortisol after hypertonic saline infusion in patients with central diabetes insipidus.
  92. Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase.
  93. Noninvasive determination of spatially resolved and time-resolved tissue perfusion in humans during nitric oxide inhibition and inhalation by use of a visible-reflectance hyperspectral imaging technique.
  94. Activation of central melanocortin receptors by MT-II increases cavernosal pressure in rabbits by the neuronal release of NO.
  95. Assimilation and catabolism of dispensable and indispensable free amino acids in post-larval Senegal sole (Solea senegalensis).
  96. Cardiovascular risk factors as determinants of endothelium-dependent and endothelium-independent vascular reactivity in the general population.
  97. Evaluation of impaired left ventricular ejection fraction and increased dimensions by multiple neurohumoral plasma concentrations.
  98. Mixture of N-carbamoyl-L-glutamate plus L-arginine can protect rats with liver cirrhosis from acute ammonia intoxication.
  99. Noninvasive detection of endothelial dysfunction in elderly with NIDDM by ultrasonography.
  100. Characterization of human liver thermostable phenol sulfotransferase (SULT1A1) allozymes with 3,3',5-triiodothyronine as the substrate.
  101. Molecular characterization of ionizing radiation-hypersensitive mutant M10 cells.
  102. The vasorelaxant hormone relaxin induces changes in liver sinusoid microcirculation: a morphologic study in the rat.
  103. Uric acid is closely linked to vascular nitric oxide activity. Evidence for mechanism of association with cardiovascular disease.
  104. Bradykinin infusion in chronic cardiac failure and the effects of captopril.
  105. The 1.6 A crystal structure of E. coli argininosuccinate synthetase suggests a conformational change during catalysis.
  106. Inhibition of nitric oxide synthase reverses changes in peritoneal permeability in a rat model of acute peritonitis.
  107. Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure.
  108. Lysine(164)alpha of protein farnesyltransferase is important for both CaaX substrate binding and catalysis.
  109. Interaction of 3-hydroxybenzoate with 3-hydroxybenzoate-6-hydroxylase.
  110. Selective activation of the 20 S proteasome (multicatalytic proteinase complex) by histone h3.
  111. Pathogenesis of primary defects in mitochondrial ATP synthesis.
  112. Role of nitric oxide in catalepsy and hyperthermia in morphine-dependent rats.
  113. Time-dependent reduction of acetylcholine-induced relaxation in aortic rings of cholestatic rats.
  114. Cytokine-induced metabolic dysfunction of MIN6 beta cells is nitric oxide independent.
  115. Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.
  116. Isolation, quantitation, and characterization of a stable complex formed by Lp[a] binding to triglyceride-rich lipoproteins.
  117. Crystal structure of an antigen-binding fragment bound to single-stranded DNA.
  118. Short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin and proteins.
  119. Functional and compositional studies of arteries stored in University of Wisconsin solution compared with Krebs-Bulbring buffer.
  120. Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin alpha-sarcin.
  121. Localization of nitric oxide synthase activity in unfertilized oocytes and fertilized embryos during preimplantation development in mice.
  122. Comparison of vaginal aminopeptidase enzymatic activities in various animals and in humans.
  123. Enuresis.
  124. Effects of regional phentolamine on hypoxic vasodilatation in healthy humans.
  125. An in vivo nitric oxide clamp to investigate the influence of nitric oxide on continuous umbilical blood flow during acute hypoxaemia in the sheep fetus.
  126. The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae.
  127. Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.
  128. Growth of conifer seedlings on organic and inorganic nitrogen sources.
  129. Characterization and expression of murine PRELP.
  130. Factor X activator from Vipera lebetina snake venom, molecular characterization and substrate specificity.
  131. Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat.
  132. Isolation and properties of arginase from a shade plant, ginseng (Panax ginseng C.A. Meyer) roots.
  133. Regulation of nitric oxide production by murine peritoneal macrophages treated in vitro with chemokine monocyte chemoattractant protein 1.
  134. Lipopolysaccharide temporarily impairs sphincter of Oddi motility.
  135. Mechanisms of synergistic cytokine-induced nitric oxide production in human alveolar epithelial cells.
  136. Nitric oxide inhibition enhances platelet aggregation in experimental anti-Thy-1 nephritis.
  137. Role of nitric oxide in the development of retinal projections.
  138. Vitamin E alleviates renal injury, but not hypertension, during chronic nitric oxide synthase inhibition in rats.
  139. Transduction of human catalase mediated by an HIV-1 TAT protein basic domain and arginine-rich peptides into mammalian cells.
  140. Effects of nitric oxide and hydrogen peroxide on histamine release from RBL-2H3 cells.
  141. Effects of nitric oxide donor and inhibitor on prostaglandin E2-like activity, malondialdehyde and reduced glutathione levels after skeletal muscle ischemia-reperfusion.
  142. Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.
  143. Endogenous endothelin and vasopressin support blood pressure during epidural anesthesia in conscious dogs.
  144. The in vitro reversal of histamine-induced vasodilation in the human internal mammary artery.
  145. The effect of repeated sublethal ischemia on NO/cGMP signal transduction system in gray matter of the rabbit spinal cord.
  146. Resistance to activated protein C--frequent etiologic factor for venous thrombosis.
  147. Metastatic melanoma cells escape from immunosurveillance through the novel mechanism of releasing nitric oxide to induce dysfunction of immunocytes.
  148. Evaluation of BacT/ALERT system for detection of Mycoplasma hominis in simulated blood cultures.
  149. Laribacter hongkongensis gen. nov., sp. nov., a novel gram-negative bacterium isolated from a cirrhotic patient with bacteremia and empyema.
  150. Mutations in subunit C of the vacuolar ATPase confer resistance to bafilomycin and identify a conserved antibiotic binding site.
  151. The novel human protein arginine N-methyltransferase PRMT6 is a nuclear enzyme displaying unique substrate specificity.
  152. Activation of endothelial cell IK(Ca) with 1-ethyl-2-benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery.
  153. Therapeutic potential of a novel synthetic selectin blocker, OJ-R9188, in allergic dermatitis.
  154. Effects of sepsis on mast cells in rat dura mater: influence of L-NAME and VIP.
  155. Exhaled nitric oxide after inhalation of isotonic and hypotonic solutions in healthy subjects.
  156. Flow-mediated dilatation following wrist and upper arm occlusion in humans: the contribution of nitric oxide.
  157. Mechanism of reaction of hydrogen peroxide with horseradish peroxidase: identification of intermediates in the catalytic cycle.
  158. Effects of phosphorylation and mutation R145G on human cardiac troponin I function.
  159. Study of asparagine 353 in aminopeptidase A: characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases.
  160. Collagen II containing a Cys substitution for Arg-alpha1-519: abnormal interactions of the mutated molecules with collagen IX.
  161. O-acetylsalicylhydroxamic acid, a novel acetylating inhibitor of prostaglandin H2 synthase: structural and functional characterization of enzyme-inhibitor interactions.
  162. An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2Y11 receptors.
  163. Role of aspartate7.32(302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation.
  164. Rhodopsin-transducin interface: studies with conformationally constrained peptides.
  165. Phenotypes associated with replacement of His by Arg in the Pendred syndrome gene.
  166. Inhibition of different types of nitric oxide synthase: effect on thermoregulation in the rat exposed to high ambient temperature.
  167. A normal rate of cellular cholesterol removal can be mediated by plasma from a patient with familial lecithin-cholesterol acyltransferase (LCAT) deficiency.
  168. Global transcriptional response of Bacillus subtilis to heat shock.
  169. Display of passenger proteins on the surface of Escherichia coli K-12 by the enterohemorrhagic E. coli intimin EaeA.
  170. Selected contribution: Effects of sex and ovariectomy on responses to platelets in porcine femoral veins.
  171. Androgen-receptor defect abolishes sex differences in nitric oxide and reactivity to vasopressin in rat aorta.
  172. Effect of estrogen on flow-induced dilation in NO deficiency: role of prostaglandins and EDHF.
  173. Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration.
  174. Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.
  175. Calculated background elimination in quantifying nitric-oxide synthase enzyme activity.
  176. The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins.
  177. Intact osmoregulatory centers in the preterm ovine fetus: Fos induction after an osmotic challenge.
  178. Increased inactivation of nitric oxide is involved in impaired coronary flow reserve in heart failure.
  179. Arteriogenesis and angiogenesis in rat ischemic hindlimb: role of nitric oxide.
  180. Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension.
  181. No involvement of nitric oxide in the limitation of beta-adrenergic inotropic responsiveness during ischemia.
  182. Integrin-binding peptides containing RGD produce coronary arteriolar dilation via cyclooxygenase activation.
  183. Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses.
  184. NMDA-mediated increase in renal sympathetic nerve discharge within the PVN: role of nitric oxide.
  185. Modulation of liver mitochondrial NOS is implicated in thyroid-dependent regulation of O(2) uptake.
  186. Mechanisms whereby rapid RV pacing causes LV dysfunction: perfusion-contraction matching and NO.
  187. Bioenergetics in cardiac hypertrophy: mitochondrial respiration as a pathological target of NO*.
  188. Effects of nebivolol on human platelet aggregation.
  189. Prevention of Porphyromonas gingivalis-induced oral bone loss following immunization with gingipain R1.
  190. Host response to infection: the role of CpG DNA in induction of cyclooxygenase 2 and nitric oxide synthase 2 in murine macrophages.
  191. Lysine and polyamines are substrates for transglutamination of Rho by the Bordetella dermonecrotic toxin.
  192. Arginine-143 of Yersinia enterocolitica YopP crucially determines isotype-related NF-kappaB suppression and apoptosis induction in macrophages.
  193. Role for inducible nitric oxide synthase in protection from chronic Chlamydia trachomatis urogenital disease in mice and its regulation by oxygen free radicals.
  194. Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.
  195. Progesterone does not alter osmotic regulation of AVP.
  196. Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP.
  197. Characterization of mechanosensitive splanchnic nerve afferent fibers innervating the rat stomach.
  198. Crystal structure and assembly of a eukaryotic small heat shock protein.
  199. An integrated proposal to explain the epidemic of cardiovascular disease in a developing country. From socioeconomic factors to free radicals.
  200. A transcriptional switch mediated by cofactor methylation.
  201. Activation of mitogenic and antimitogenic pathways in cyclically stretched arterial smooth muscle.